We are exploring enzymes that evolve new functions in changing environments, with a particular interest in enzymes that interact with and degrade natural and synthetic polymers. Using experimental and computational approaches, we investigate the molecular and evolutionary mechanisms that govern enzyme adaptation, structure-function relationships, and microbial interactions. We are especially interested in understanding how enzymes recognize, bind, and function at polymer and plastic surfaces, and how environmental conditions shape the evolution of these activities. By uncovering the fundamental principles underlying enzyme evolution and polymer degradation, we aim to advance basic biological knowledge while enabling the development of sustainable enzymatic solutions for biotechnology and environmental challenges..

We are intrested in how enzymes evolve new functions and substrate specificities in response to changing environments, and how these evolutionary processes influence microbial communication and adaptation. Using experimental and computational approaches, we study the fundamental principles that govern enzyme evolution, structure-function relationships, and microbial interactions. Understanding these mechanisms not only advances basic science but also enables the rational development of enzymes for applications in health, agriculture, biotechnology, and environmental sustainability.